Because most cases of Addison’s disease are autoimmune, people with Addison’s disease may also develop vitiligo. People with one autoimmune disease are more at risk of developing another. A person with adrenal insufficiency feels weak, tired, and dizzy when standing up after sitting or lying down, and may develop dark skin patches. It may also affect hair color and the hair in the inner ear. Smooth white patches of skin appear as the immune system destroys the skin cells that make melanin. Vitiligo is an autoimmune disease that causes the skin to lose its color. Cancerous adrenal tumors can be functional and release excess of one or more hormones accompanied by corresponding symptoms, as listed above. The discoloration develops over a variety of areas, including:ĭark patches usually develop first in the mouth and gums, along with blue-black patches across the genitals and rectum, before they appear across the body. The appearance of dark patches on the skin is a common symptom of Addison’s disease. There are several Addison’s disease symptoms, which include: Hyperpigmentation Signs and symptoms of Addison's disease in your skinĪddison’s disease usually progresses slowly and isn’t recognized until another illness or intense stress suddenly makes it worse.
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